Nothing that I’ve noticed. And Proton runs everything I want to play. The back buttons are used for the bazzite overlay. That took some time to get used to. But aside from that it was a smooth experience and I would never change back. It got me to switch from Windows to Bazzite on my desktop. But that was a whole different thing with the Nvidia Wayland Firefox problems a few months ago.

Complete wipe. And it was easy without any hassle out of the box.

I have Bazzite running my Legion Go. The experience is so much better in its Steam Deck like frontend than the Windows 11/Legion App combo. And the desktop mode makes it a fully functioning desktop PC as well, if it is needed. All in all one of the smoothest experiences in terms of switching to Bazzite.